Abstract
Many advances continue to be made in the field of plant-derived vaccines. Plants have been shown capable of expressing a multicomponent vaccine that when orally delivered induces a T-helper cell subset 1 response and enables passive immunization. Furthermore, a plant-derived vaccine has been shown to protect against challenge in the target host. Increased antigen expression levels (up to 4.1% total soluble protein) have been obtained through transformation of the chloroplast genome. In view of these findings, plant-derived vaccines have been proved as valuable commodities to the world's health system; however, before their application, studies need to focus on optimization of immunization strategies and to investigate antigen stability.
Original language | English (US) |
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Pages (from-to) | 145-150 |
Number of pages | 6 |
Journal | Current Opinion in Biotechnology |
Volume | 14 |
Issue number | 2 |
DOIs | |
State | Published - Apr 2003 |
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Biomedical Engineering