Photosystem I reaction-centre proteins contain leucine zipper motifs. A proposed role in dimer formation

Andrew N. Webber, Richard Malkin

Research output: Contribution to journalArticle

37 Scopus citations

Abstract

The photosystem I (PS I) reaction-centre polypeptides, encoded by the psaA and psaB genes, are shown to contain several highly conserved leucine repeats, consisting of a leucine residue every seventh amino acid, similar to the leucine zipper motifs known to mediate DNA-binding polypeptide dimerisation. In each of the PSI reaction-centre subunits the leucine zipper motif precedes highly conserved cysteine residues which have been proposed to ligate the interpolypeptide [4Fe-4S] centre, Fx. We propose that PS I reaction-centre dimerisation and [4Fe-4S] centre formation are mediated through the leucine zipper.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalFEBS Letters
Volume264
Issue number1
DOIs
StatePublished - May 7 1990

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Keywords

  • Iron-sulphur center
  • Leucine zipper
  • Photosystem I
  • Reaction center

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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