Phosphorylation and Mutation of Human Cardiac Troponin I Deferentially Destabilize the Interaction of the Functional Regions of Troponin I with Troponin C

Medicine & Life Sciences

• Troponin C 100%
• Troponin I 80%
• Familial Hypertrophic Cardiomyopathy 61%
• Phosphorylation 46%
• Mutation 38%
• sprodiamide 37%
• Cardiomyopathy, Familial Hypertrophic, 2 22%
• Protein Kinase C 18%
• p21-Activated Kinases 13%
• Myofibrils 11%
• Muscle Contraction 10%
• Magnetic Resonance Spectroscopy 8%
• Myocardium 8%

Chemical Compounds

• Mutation 57%
• 1H-15N HSQC 14%
• Protein 8%
• NMR Spectroscopy 6%
• Modification 5%