Phenotypic modulation of gonococcal lipooligosaccharide in acidic and alkaline culture

R. K. Pettit, E. S. Martin, S. M. Wagner, V. J. Bertolino

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Neisseria gonorrhoeae infects a diverse array of niches in its human host, which expose the organism to dramatic variations in pH. We examined growth and lipooligosaccharide expression of two gonococcal strains in liquid and solid cultures under acidic, neutral, and alkaline conditions. Growth rates in broth were similar under the three conditions, and the pH remained fairly constant throughout the growth cycle. Altered lipooligosaccharide expression at the different pHs was noted in both plate- and broth-grown organisms.

Original languageEnglish (US)
Pages (from-to)2773-2775
Number of pages3
JournalInfection and immunity
Issue number7
StatePublished - 1995
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases


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