Pharmacokinetic and Pharmacodynamic Properties of Mycophenolate

David Hager, Arjang Djamali, Bruce Kaplan

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Abstract

    This chapter serves as a starting point for clinicians and researchers providing the necessary background as well as future directions and applications of the available pharmacodynamic studies in therapeutic drug monitoring. A brief history of mycophenolate and the current understanding of its multiple mechanisms of action are included, as are a review of its preclinical and clinical data. Areas for additional necessary research are described.

    Original languageEnglish (US)
    Title of host publicationImmunotherapy in Transplantation
    Subtitle of host publicationPrinciples and Practice
    PublisherWiley-Blackwell
    Pages182-196
    Number of pages15
    ISBN (Print)9781405182713
    DOIs
    StatePublished - Apr 19 2012

    Keywords

    • Drug interactions
    • Graft rejection prevention and control
    • IMP dehydrogenase antagonists and inhibitors
    • Mycophenolic acid
    • Pharmacodynamics
    • Pharmacogenomics
    • Pharmacokinetics
    • Therapeutic drug monitoring

    ASJC Scopus subject areas

    • Medicine(all)

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  • Cite this

    Hager, D., Djamali, A., & Kaplan, B. (2012). Pharmacokinetic and Pharmacodynamic Properties of Mycophenolate. In Immunotherapy in Transplantation: Principles and Practice (pp. 182-196). Wiley-Blackwell. https://doi.org/10.1002/9781444355628.ch14