Abstract
This chapter serves as a starting point for clinicians and researchers providing the necessary background as well as future directions and applications of the available pharmacodynamic studies in therapeutic drug monitoring. A brief history of mycophenolate and the current understanding of its multiple mechanisms of action are included, as are a review of its preclinical and clinical data. Areas for additional necessary research are described.
Original language | English (US) |
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Title of host publication | Immunotherapy in Transplantation |
Subtitle of host publication | Principles and Practice |
Publisher | Wiley-Blackwell |
Pages | 182-196 |
Number of pages | 15 |
ISBN (Print) | 9781405182713 |
DOIs | |
State | Published - Apr 19 2012 |
Keywords
- Drug interactions
- Graft rejection prevention and control
- IMP dehydrogenase antagonists and inhibitors
- Mycophenolic acid
- Pharmacodynamics
- Pharmacogenomics
- Pharmacokinetics
- Therapeutic drug monitoring
ASJC Scopus subject areas
- General Medicine