Pertussis in an adult man infected with the human immunodeficiency virus

Bradley N. Doebbeling, Mary Lou Feilmeier, Loreen A. Herwaldt

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


A 25-year-old man infected with the human immunodeficiency virus (HIV) presented with paroxysmal cough and dyspnea of 4-months duration. An extensive evaluation including bronchoscopy was negative. A nasopharyngeal swab was positive by direct fluorescent antigen detection and culture for Bordetella pertussis. Respiratory isolation, treatment with erythromycin, and prophylaxis of household contacts was used to eradicate the organism and prevent transmission. Pertussis should be considered as a cause of prolonged cough and dyspnea in patients with HIV infection. The course ofthis patient was consistent with the concept that cell-mediated immunity is necessary for elimination of B. pertussis.

Original languageEnglish (US)
Pages (from-to)1296-1298
Number of pages3
JournalJournal of Infectious Diseases
Issue number6
StatePublished - Jun 1990
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases


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