PD-1 blockade: Rescue from a near-death experience

Joseph N. Blattman, Philip D. Greenberg

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

It is unclear whether T cell exhaustion is reversible. A recent Nature paper shows that in vivo blockade of the inhibitory molecule PD-1 can restore the function of exhausted CD8+ T cells during chronic viral infection.

Original languageEnglish (US)
Pages (from-to)227-228
Number of pages2
JournalNature Immunology
Volume7
Issue number3
DOIs
StatePublished - Mar 2006
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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