Passive mixing in microchannels: Fabrication and flow experiments

David J. Beebe, Ronald Adrian, Michael G. Olsen, Mark A. Stremler, Hassan Aref, Byung Ho Jo

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

Obtaining rapid mixing in microfluidic systems is a problem that must continue to be addressed if microelectromechanical systems are to attain their full potential in commercial markets. We present the paradigm of "designing for chaos" as a general framework for enhancing mixing in microfluidic applications. Designing for chaos is based on a fundamental understanding of the kinematics underlying the mixing process, freeing the MEMS researcher to work with design guidelines instead of empirically determined physical configurations. We have applied this strategy in designing a passive in-line micromixer that relies on three degrees of freedom to create chaos. The mixer design was fabricated using a compression micromolding process to create three-dimensional flow channels in polydimethylsiloxane (PDMS). Computational and experimental analyses demonstrate the effectiveness of the resulting design in generating chaos in the flow and hence enhancing mixing.

Original languageEnglish (US)
Pages (from-to)343-348
Number of pages6
JournalMecanique et Industries
Volume2
Issue number4
DOIs
StatePublished - Jul 2001
Externally publishedYes

Fingerprint

Microchannels
Chaos theory
Fabrication
Microfluidics
MEMS
Experiments
Polydimethylsiloxane
Channel flow
Kinematics

Keywords

  • Expériences
  • Experiments
  • Mélange
  • Microcanaux
  • Microchannels
  • Mixing

ASJC Scopus subject areas

  • Mechanical Engineering
  • Materials Science(all)

Cite this

Passive mixing in microchannels : Fabrication and flow experiments. / Beebe, David J.; Adrian, Ronald; Olsen, Michael G.; Stremler, Mark A.; Aref, Hassan; Jo, Byung Ho.

In: Mecanique et Industries, Vol. 2, No. 4, 07.2001, p. 343-348.

Research output: Contribution to journalArticle

Beebe, David J. ; Adrian, Ronald ; Olsen, Michael G. ; Stremler, Mark A. ; Aref, Hassan ; Jo, Byung Ho. / Passive mixing in microchannels : Fabrication and flow experiments. In: Mecanique et Industries. 2001 ; Vol. 2, No. 4. pp. 343-348.
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