Partitioned method of valid moment marginal model with Bayes interval estimates for correlated binary data with time-dependent covariates

Elsa Vazquez, Jeffrey R. Wilson

Research output: Contribution to journalArticlepeer-review

Abstract

The fit of marginal models to longitudinal data should include modelling all extra variation among responses and covariates. This paper proposes a Partitioned Method of Valid Moments marginal regression model for binary outcomes with Bayes method while using lagged coefficients. Time-dependent covariates are factored in through composite likelihoods. A simulation study highlights the properties of the model coefficients. Modeling cognitive impairment diagnosis in NACC Alzheimer clinical data are demonstrated. Sensitivity analyses are conducted to evaluate the impact of the prior distribution on the posterior inferences.

Original languageEnglish (US)
Pages (from-to)2701-2718
Number of pages18
JournalComputational Statistics
Volume36
Issue number4
DOIs
StatePublished - Dec 2021

Keywords

  • Bayes interval estimates
  • Binary outcomes
  • Logistic regression
  • Longitudinal data
  • Valid moments

ASJC Scopus subject areas

  • Statistics and Probability
  • Statistics, Probability and Uncertainty
  • Computational Mathematics

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