Parental psychopathology and disorders in offspring: A study of relatives of drug abusers

Suniya Luthar, K. R. Merikangas, B. J. Rounsaville

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Associations between psychopathology among parents and among their offspring were examined among families of drug abusers. Patterns of transmission of disorders were examined in the context of several potential moderator variables, including gender of parent, ethnicity, and type of drug abused by the proband relative. The sample consisted of 492 parents and 673 siblings of cocaine abusers, and 400 parents and 476 siblings of opioid addicts. Results indicated that a) maternal depression was associated with several psychiatric disorders among all groups of offspring; b) paternal alcoholism yielded less powerful effects, showing associations with offspring substance abuse among blacks but not Caucasians; c) incidence of disorders among offspring showed sequential increases depending on whether neither, one, or both parents were affected; and d) there was little evidence for specificity of aggregation of disorders among these families. Results are discussed in terms of implications for empirical studies as well as intervention programming.

Original languageEnglish (US)
Pages (from-to)351-357
Number of pages7
JournalJournal of Nervous and Mental Disease
Volume181
Issue number6
DOIs
StatePublished - 1993
Externally publishedYes

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Drug Users
Psychopathology
Parents
Siblings
Epidemiologic Effect Modifiers
Cocaine
Opioid Analgesics
Alcoholism
Substance-Related Disorders
Psychiatry
Mothers
Depression
Incidence
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Parental psychopathology and disorders in offspring : A study of relatives of drug abusers. / Luthar, Suniya; Merikangas, K. R.; Rounsaville, B. J.

In: Journal of Nervous and Mental Disease, Vol. 181, No. 6, 1993, p. 351-357.

Research output: Contribution to journalArticle

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