Overview of Biochemical Assays in Lipidic Cubic Phase

Zhu Lan; Ming Yue Lee; Eugene Chun; Bin Liu; Wei Liu

doi:10.1016/j.tibs.2018.08.008

Overview of Biochemical Assays in Lipidic Cubic Phase

Zhu Lan, Ming Yue Lee, Eugene Chun, Bin Liu, Wei Liu

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The development of novel biochemical methods to efficiently characterize membrane protein (MP) properties in lipidic cubic phase (LCP) is important for studying complicated MPs and their multimeric complexes. Here, we summarize recent LCP-related assays and provide an outlook on their applications in structure and function studies of MPs.

Original language	English (US)
Journal	Trends in Biochemical Sciences
DOIs	https://doi.org/10.1016/j.tibs.2018.08.008
State	Accepted/In press - Jan 1 2018

Keywords

crystallization
functional assay
LCP
membrane protein
protein stability

ASJC Scopus subject areas

Biochemistry
Molecular Biology

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10.1016/j.tibs.2018.08.008

Cite this

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title = "Overview of Biochemical Assays in Lipidic Cubic Phase",

abstract = "The development of novel biochemical methods to efficiently characterize membrane protein (MP) properties in lipidic cubic phase (LCP) is important for studying complicated MPs and their multimeric complexes. Here, we summarize recent LCP-related assays and provide an outlook on their applications in structure and function studies of MPs.",

keywords = "crystallization, functional assay, LCP, membrane protein, protein stability",

author = "Zhu Lan and Lee, {Ming Yue} and Eugene Chun and Bin Liu and Wei Liu",

year = "2018",

month = jan,

day = "1",

doi = "10.1016/j.tibs.2018.08.008",

language = "English (US)",

journal = "Trends in Biochemical Sciences",

issn = "0968-0004",

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T1 - Overview of Biochemical Assays in Lipidic Cubic Phase

AU - Lan, Zhu

AU - Lee, Ming Yue

AU - Chun, Eugene

AU - Liu, Bin

AU - Liu, Wei

PY - 2018/1/1

Y1 - 2018/1/1

N2 - The development of novel biochemical methods to efficiently characterize membrane protein (MP) properties in lipidic cubic phase (LCP) is important for studying complicated MPs and their multimeric complexes. Here, we summarize recent LCP-related assays and provide an outlook on their applications in structure and function studies of MPs.

AB - The development of novel biochemical methods to efficiently characterize membrane protein (MP) properties in lipidic cubic phase (LCP) is important for studying complicated MPs and their multimeric complexes. Here, we summarize recent LCP-related assays and provide an outlook on their applications in structure and function studies of MPs.

KW - crystallization

KW - functional assay

KW - LCP

KW - membrane protein

KW - protein stability

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DO - 10.1016/j.tibs.2018.08.008

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SN - 0968-0004

JO - Trends in Biochemical Sciences

JF - Trends in Biochemical Sciences

ER -

Overview of Biochemical Assays in Lipidic Cubic Phase

Abstract

Keywords

ASJC Scopus subject areas

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