Overcoming the screening-induced performance limits of nanowire biosensors: A simulation study on the effect of electro-diffusion flow

Yang Liu, Klas Lilja, Clemens Heitzinger, Robert W. Dutton

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Abstract

Device-level simulation capabilities have been developed to self-consistently model the Si-nanowire (NW) biosensor systems. Our numerical study demonstrates that by introducing electro-diffusion current flow in the electrolyte solutions, the electrostatic screening of the biological charge can be significantly suppressed; an improvement of the sensed signal strength by >≈10X is indicated. Based on such an operation principle, the screening-induced performance limits on Si-NW biosensors can be overcome.

Original languageEnglish (US)
Title of host publication2008 IEEE International Electron Devices Meeting, IEDM 2008
DOIs
StatePublished - Dec 1 2008
Event2008 IEEE International Electron Devices Meeting, IEDM 2008 - San Francisco, CA, United States
Duration: Dec 15 2008Dec 17 2008

Publication series

NameTechnical Digest - International Electron Devices Meeting, IEDM
ISSN (Print)0163-1918

Other

Other2008 IEEE International Electron Devices Meeting, IEDM 2008
CountryUnited States
CitySan Francisco, CA
Period12/15/0812/17/08

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ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Electrical and Electronic Engineering
  • Materials Chemistry

Cite this

Liu, Y., Lilja, K., Heitzinger, C., & Dutton, R. W. (2008). Overcoming the screening-induced performance limits of nanowire biosensors: A simulation study on the effect of electro-diffusion flow. In 2008 IEEE International Electron Devices Meeting, IEDM 2008 [4796733] (Technical Digest - International Electron Devices Meeting, IEDM). https://doi.org/10.1109/IEDM.2008.4796733