Abstract
Although short-term kidney graft survival has improved in recent years, the focus has shifted to the challenge of improving long-term graft survival. Acute rejection, chronic allograft nephropathy, and cardiovascular disease are associated with graft loss and patient death. Reducing the potential for such posttransplantation complications may improve long-term graft survival. In addition, gaining a better understanding of the role that various immunosuppressive therapies have in decreasing the risk for graft injury will help clinicians make better-informed decisions about appropriate treatment regimens for individual kidney transplant recipients.
Original language | English (US) |
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Pages (from-to) | S52-S64 |
Journal | American Journal of Kidney Diseases |
Volume | 47 |
Issue number | 4 SUPPL. 2 |
DOIs | |
State | Published - Apr 2006 |
Keywords
- Acute rejection
- Chronic allograft nephropathy (CAN)
- Cyclosporine (CsA)
- Graft survival
- Immunosuppression
- Kidney transplant
- Mycophenolate mofetil (MMF)
- Renal function
- Sirolimus (SRL)
- Tacrolimus (TAC)
ASJC Scopus subject areas
- Nephrology