Abstract
For a single patch SIRS model with a period of immunity of fixed length, recruitment-death demographics, disease related deaths and mass action incidence, the basic reproduction number R0 is identified. It is shown that the disease-free equilibrium is globally asymptotically stable if R0 < 1. For R0 > 1, local stability of the endemic equilibrium and Hopf bifurcation analysis about this equilibrium are carried out. Moreover, a practical numerical approach to locate the bifurcation values for a characteristic equation with delay-dependent coefficients is provided. For a two patch SIRS model with travel, it is shown that there are several threshold quantities determining its dynamic behavior and that travel can reduce oscillations in both patches; travel may enhance oscillations in both patches; or travel can switch oscillations from one patch to another.
Original language | English (US) |
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Pages (from-to) | 1-10 |
Number of pages | 10 |
Journal | Mathematical Biosciences |
Volume | 215 |
Issue number | 1 |
DOIs | |
State | Published - Sep 2008 |
Externally published | Yes |
Keywords
- Basic reproduction number
- Delay
- Global asymptotic stability
- Hopf bifurcation
- Oscillation
- Travel between patches
ASJC Scopus subject areas
- Statistics and Probability
- Modeling and Simulation
- Biochemistry, Genetics and Molecular Biology(all)
- Immunology and Microbiology(all)
- Agricultural and Biological Sciences(all)
- Applied Mathematics