Optimization of solvent mixture compositions for high speed countercurrent distribution

D. Kantoci, George Pettit, Z. Cichacz

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Seven solvents considered appropriate for use with relatively sensitive biosynthetic products undergoing separation by multilayer coil planet centrifuge high speed countercurrent distribution (HSCCD) have been evaluated in a new and systematic procedure for optimal solvent selection. The new method was illustrated by a complete HSCCD separation of five closely related dipeptides.

Original languageEnglish (US)
Pages (from-to)1149-1160
Number of pages12
JournalJournal of Liquid Chromatography
Volume14
Issue number6
DOIs
StatePublished - Mar 1 1991

ASJC Scopus subject areas

  • Molecular Medicine

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