Optical detection of structural changes in atherosclerotic plaque

R. M. Korol, P. B. Canham, H. M. Finlay, R. R. Hammond, M. Quantz, G. G. Ferguson, A. R. Lucas

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have demonstrated that in vitro fluorescence spectroscopic analysis of diseased carotid arteries can identify clinically relevant compositional changes in connective tissue (collagen type I, III, IV and elastin) associated with plaque remodeling and instability.

Original languageEnglish (US)
Title of host publicationEuropean Conference on Biomedical Optics, ECBO 2005
PublisherOptical Society of America
ISBN (Print)0819458635, 9780819458636
StatePublished - 2005
Externally publishedYes
EventEuropean Conference on Biomedical Optics, ECBO 2005 - Munich, Germany
Duration: Jun 12 2005Jun 12 2005

Publication series

NameOptics InfoBase Conference Papers
ISSN (Electronic)2162-2701

Conference

ConferenceEuropean Conference on Biomedical Optics, ECBO 2005
CountryGermany
CityMunich
Period6/12/056/12/05

Keywords

  • Atherosclerosis
  • Collagen
  • Elastin
  • Fluorescence spectroscopy
  • Plaque morphology
  • Vascular remodeling

ASJC Scopus subject areas

  • Instrumentation
  • Atomic and Molecular Physics, and Optics

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