TY - JOUR
T1 - Once-daily feeding is associated with better health in companion dogs
T2 - results from the Dog Aging Project
AU - Dog Aging Project Consortium
AU - Bray, Emily E.
AU - Zheng, Zihan
AU - Tolbert, M. Katherine
AU - McCoy, Brianah M.
AU - Akey, Joshua M.
AU - Benton, Brooke
AU - Borenstein, Elhanan
AU - Castelhano, Marta G.
AU - Coleman, Amanda E.
AU - Creevy, Kate E.
AU - Crowder, Kyle
AU - Dunbar, Matthew D.
AU - Fajt, Virginia R.
AU - Fitzpatrick, Annette L.
AU - Jeffrey, Unity
AU - Jonlin, Erica C.
AU - Karlsson, Elinor K.
AU - Levine, Jonathan M.
AU - Ma, Jing
AU - McClelland, Robyn L.
AU - Promislow, Daniel E.L.
AU - Ruple, Audrey
AU - Schwartz, Stephen M.
AU - Shrager, Sandi
AU - Snyder-Mackler, Noah
AU - Urfer, Silvan R.
AU - Wilfond, Benjamin S.
AU - Kaeberlein, Matt
AU - Kerr, Kathleen F.
N1 - Publisher Copyright:
© 2022, The Author(s), under exclusive licence to American Aging Association.
PY - 2022/6
Y1 - 2022/6
N2 - A variety of diets have been studied for possible anti-aging effects. In particular, studies of intermittent fasting and time-restricted feeding in laboratory rodents have found evidence of beneficial health outcomes. Companion dogs represent a unique opportunity to study diet in a large mammal that shares human environments. The Dog Aging Project has been collecting data on thousands of companion dogs of all different ages, sizes, and breeds since 2019. We leveraged this diverse cross-sectional dataset to investigate associations between feeding frequency and cognitive function (n = 10,474) as well as nine broad categories of health conditions (n = 24,238). Controlling for sex, age, breed, and other potential confounders, we found that dogs fed once daily rather than more frequently had lower mean scores on a cognitive dysfunction scale, and lower odds of having gastrointestinal, dental, orthopedic, kidney/urinary, and liver/pancreas disorders. Therefore, we find that once-daily feeding is associated with better health in multiple domains. Future research with longitudinal data can provide stronger evidence for a possible causal effect of feeding frequency on health in companion dogs.
AB - A variety of diets have been studied for possible anti-aging effects. In particular, studies of intermittent fasting and time-restricted feeding in laboratory rodents have found evidence of beneficial health outcomes. Companion dogs represent a unique opportunity to study diet in a large mammal that shares human environments. The Dog Aging Project has been collecting data on thousands of companion dogs of all different ages, sizes, and breeds since 2019. We leveraged this diverse cross-sectional dataset to investigate associations between feeding frequency and cognitive function (n = 10,474) as well as nine broad categories of health conditions (n = 24,238). Controlling for sex, age, breed, and other potential confounders, we found that dogs fed once daily rather than more frequently had lower mean scores on a cognitive dysfunction scale, and lower odds of having gastrointestinal, dental, orthopedic, kidney/urinary, and liver/pancreas disorders. Therefore, we find that once-daily feeding is associated with better health in multiple domains. Future research with longitudinal data can provide stronger evidence for a possible causal effect of feeding frequency on health in companion dogs.
KW - Canine
KW - Canine cognitive dysfunction
KW - Feeding frequency
KW - Healthy aging
KW - Time-restricted feeding
UR - http://www.scopus.com/inward/record.url?scp=85132453786&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85132453786&partnerID=8YFLogxK
U2 - 10.1007/s11357-022-00575-7
DO - 10.1007/s11357-022-00575-7
M3 - Article
C2 - 35484470
AN - SCOPUS:85132453786
SN - 2509-2715
VL - 44
SP - 1779
EP - 1790
JO - GeroScience
JF - GeroScience
IS - 3
ER -