On the potential for molecular imaging with Cerenkov luminescence

Matthew A. Lewis, Vikram D. Kodibagkar, Orhan K. Öz, Ralph P. Mason

Research output: Contribution to journalArticle

61 Scopus citations

Abstract

Recent observation of optical luminescence due to beta decay from suitable radiotracers has led to the possible development of new preclinical optical imaging methods. The generation of photons that can be detected using instrumentation optimized for bioluminescence imaging has been putatively associated with the Cerenkov effect. We describe the simultaneous utilization of fluorescence reporters to convert Cerenkov luminescence to longer wavelengths for better tissue penetration and also for modulating the luminescence spectrum for potential molecular imaging strategies.

Original languageEnglish (US)
Pages (from-to)3889-3891
Number of pages3
JournalOptics Letters
Volume35
Issue number23
DOIs
StatePublished - Dec 1 2010

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ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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