On-chip cell culture biosensing with microfluidic feedback control

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present work towards expanding the capabilities of microfluidic cell culture devices through the incorporation of microelectronic sensing systems. A system has been fabricated that includes four sensing regions each consisting of a pH sensor, capacitance sensor, and photodiode. We have demonstrated the incorporation of feedback control systems using computer controlled microfluidics for a pH sensor. Preliminary data for photodiode characterization, pH detection using ISFETs, and capacitance sensing of cell density is presented. Results from this work will be used towards creating a single system that can function as a cell culture platform with programmable control over all of these variables.

Original languageEnglish (US)
Title of host publicationProceedings of the 2011 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2011
Pages39-42
Number of pages4
DOIs
StatePublished - May 23 2011
Event2011 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2011 - Bethesda, MD, United States
Duration: Apr 7 2011Apr 8 2011

Publication series

NameProceedings of the 2011 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2011

Other

Other2011 IEEE/NIH Life Science Systems and Applications Workshop, LiSSA 2011
CountryUnited States
CityBethesda, MD
Period4/7/114/8/11

ASJC Scopus subject areas

  • Life-span and Life-course Studies

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