Numerical modeling of the transmission dynamics of drug-sensitive and drug-resistant HSV-2

Research output: Contribution to journalArticle

Abstract

A competitive finite-difference method will be constructed and used to solve a modified deterministic model for the spread of herpes simplex virus type-2 (HSV-2) within a given population. The model monitors the transmission dynamics and control of drug-sensitive and drug-resistant HSV-2. Unlike the fourth-order Runge-Kutta method (RK4), which fails when the discretization parameters exceed certain values, the novel numerical method to be developed in this paper gives convergent results for all parameter values.

Original languageEnglish (US)
Pages (from-to)23-27
Number of pages5
JournalCommunications in Nonlinear Science and Numerical Simulation
Volume6
Issue number1
DOIs
StatePublished - Jan 1 2001
Externally publishedYes

Keywords

  • Finite-difference
  • HSV-2
  • Initial-value problem
  • Numerical instabilities
  • Positivity

ASJC Scopus subject areas

  • Numerical Analysis
  • Modeling and Simulation
  • Applied Mathematics

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