Numerical modeling of the effect of field configurations on the magnetic nanoparticle delivery system

Muralidhar K. Ghantasala, Pavel Ikonomov, Tijana Rajh, Allan David, Ahmed Albaghly, Abdullah Alghulam, Ibraheem Kaseb

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper presents the details of our studies on the numerical modeling of magnetic nanoparticle drug delivery using Ferrohydrodynamics based numerical models. The magnetic field and fluid flow were governed by Maxwell and the Navier-Stokes equations. A magnetic volume force couples the magnetic field to a fluid-flow problem in the blood-vessel domain described by the Navier-Stokes equations. The magnetic field generates magnetic volume forces that affect the flow field in the blood vessel. The fluid has the properties of blood (e.g. viscosity, flow rate and others) and magnetic characteristics of nanoparticles and hence becomes a ferrofluid. This helped in understanding the effect of variation of magnetic field distribution on the fluid velocity profiles. Two different field configurations, with symmetric and asymmetric pole fields, were considered and the fluid velocities in different gradient fields were compared. The results clearly showed that the fluid velocity decreased as the magnetic field increased.

Original languageEnglish (US)
Title of host publicationBiotech, Biomaterials and Biomedical - TechConnect Briefs 2016
EditorsMatthew Laudon, Fiona Case, Fiona Case, Bart Romanowicz, Bart Romanowicz
PublisherTechConnect
Pages169-172
Number of pages4
ISBN (Electronic)9780997511727
StatePublished - 2016
Externally publishedYes
Event10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 19th Annual Nanotech Conference and Expo, and the 2016 National SBIR/STTR Conference - Washington, United States
Duration: May 22 2016May 25 2016

Publication series

NameAdvanced Materials - TechConnect Briefs 2016
Volume3

Other

Other10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 19th Annual Nanotech Conference and Expo, and the 2016 National SBIR/STTR Conference
Country/TerritoryUnited States
CityWashington
Period5/22/165/25/16

Keywords

  • Comsol
  • Magnetic nanoparticle
  • Maxwell equations
  • Nano drug delivery
  • Navier-Stokes equation

ASJC Scopus subject areas

  • Fluid Flow and Transfer Processes
  • Biotechnology
  • Surfaces, Coatings and Films
  • Fuel Technology

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