TY - JOUR
T1 - Nosocomial Legionella micdadei pneumonia
T2 - 10 years experience and a case-control study
AU - Doebbeling, Bradley N.
AU - Ishak, Magued A.
AU - Wade, Barbara H.
AU - Pasquale, Michael A.
AU - Gerszten, Robert E.
AU - Gröschel, Dieter H.M.
AU - Kadner, Robert J.
AU - Wenzel, Richard P.
N1 - Funding Information:
was supported Foundation.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1989/4
Y1 - 1989/4
N2 - Sixteen patients with nosocomial Legionella micdadei pneumonia, diagnosed between 1977 and 1988, were studied retrospectively to define clinical and epidemiological characteristics of the disease. Also, a case-control study was performed comparing the five patients with L. micdadei pneumonia during a cluster of cases in 1982, with uninfected patients with the same underlying diagnoses. No significant differences were noted in the case-control study with regard to age, presence of leucopenia, intensity or duration of immunosuppressive therapy, bed location, duration of hospital stay, frequency of transplant rejection or overall mortality. Legionella micdadei isolates from a sink on the renal transport ward, from hot water storage tanks, and one clinical isolate had identical cellular fatty acid composition. Extensive sampling of other potential sources failed to yield the organism. This indirect evidence suggests potable water as the source of infection.
AB - Sixteen patients with nosocomial Legionella micdadei pneumonia, diagnosed between 1977 and 1988, were studied retrospectively to define clinical and epidemiological characteristics of the disease. Also, a case-control study was performed comparing the five patients with L. micdadei pneumonia during a cluster of cases in 1982, with uninfected patients with the same underlying diagnoses. No significant differences were noted in the case-control study with regard to age, presence of leucopenia, intensity or duration of immunosuppressive therapy, bed location, duration of hospital stay, frequency of transplant rejection or overall mortality. Legionella micdadei isolates from a sink on the renal transport ward, from hot water storage tanks, and one clinical isolate had identical cellular fatty acid composition. Extensive sampling of other potential sources failed to yield the organism. This indirect evidence suggests potable water as the source of infection.
KW - Pittsburgh pneumonia agent
KW - epidemiology
KW - hospital-acquired L. micdadei
KW - nosocomial legionellosis
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U2 - 10.1016/0195-6701(89)90010-8
DO - 10.1016/0195-6701(89)90010-8
M3 - Article
C2 - 2567759
AN - SCOPUS:0024315201
SN - 0195-6701
VL - 13
SP - 289
EP - 298
JO - Journal of Hospital Infection
JF - Journal of Hospital Infection
IS - 3
ER -