Nonsteroidal antiinflammatory drugs, eicosanoids, and colorectal cancer prevention

R. N. DuBois; F. M. Giardiello; W. E. Smalley

doi:10.1016/S0889-8553(05)70274-0

Nonsteroidal antiinflammatory drugs, eicosanoids, and colorectal cancer prevention

R. N. DuBois, F. M. Giardiello, W. E. Smalley

Research output: Contribution to journal › Article › peer-review

220 Scopus citations

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to be one of the most affective class of chemoprotective agents to date. Most of the published studies have evaluated gastrointestinal malignancies. Here the authors review the clinical, epidemiologic, and laboratory data evaluating the affects of NSAIDs in cancer prevention. The authors hope that through a rigorous evaluation of past work and future experimentation the molecular basis for cancer chemoprevention by these agents will be understood.

Original language	English (US)
Pages (from-to)	773-791
Number of pages	19
Journal	Gastroenterology Clinics of North America
Volume	25
Issue number	4
DOIs	https://doi.org/10.1016/S0889-8553(05)70274-0
State	Published - 1996
Externally published	Yes

ASJC Scopus subject areas

Gastroenterology

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10.1016/S0889-8553(05)70274-0

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title = "Nonsteroidal antiinflammatory drugs, eicosanoids, and colorectal cancer prevention",

abstract = "Nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to be one of the most affective class of chemoprotective agents to date. Most of the published studies have evaluated gastrointestinal malignancies. Here the authors review the clinical, epidemiologic, and laboratory data evaluating the affects of NSAIDs in cancer prevention. The authors hope that through a rigorous evaluation of past work and future experimentation the molecular basis for cancer chemoprevention by these agents will be understood.",

author = "DuBois, {R. N.} and Giardiello, {F. M.} and Smalley, {W. E.}",

note = "Funding Information: The authors would like to thank Georgia and Louise Hanson. RND would like to acknowledge support from the A. B. Hancock, Jr., Memorial Laboratory, Lucille P. Markey Charitable Trust, the US Public Health Services Grants NIHES 00267 and DK 47297, and the Veterans Administration Merit Grant. RND is a recipient of a VA Research Associate career development award and Boehringer Ingelheim New Investigator Award, and is an AGA Industry Research Scholar.",

year = "1996",

doi = "10.1016/S0889-8553(05)70274-0",

language = "English (US)",

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pages = "773--791",

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T1 - Nonsteroidal antiinflammatory drugs, eicosanoids, and colorectal cancer prevention

AU - DuBois, R. N.

AU - Giardiello, F. M.

AU - Smalley, W. E.

N1 - Funding Information: The authors would like to thank Georgia and Louise Hanson. RND would like to acknowledge support from the A. B. Hancock, Jr., Memorial Laboratory, Lucille P. Markey Charitable Trust, the US Public Health Services Grants NIHES 00267 and DK 47297, and the Veterans Administration Merit Grant. RND is a recipient of a VA Research Associate career development award and Boehringer Ingelheim New Investigator Award, and is an AGA Industry Research Scholar.

PY - 1996

Y1 - 1996

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Nonsteroidal antiinflammatory drugs, eicosanoids, and colorectal cancer prevention

Abstract

ASJC Scopus subject areas

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