Abstract

N-Nitrosodimethylamine (NDMA) is a disinfection by-product of concern in water reuse applications due to its potential human carcinogenicity. NDMA forms via the reaction of organic amine precursors with chloramines during water treatment. Advanced treatment for potable reuse reduces NDMA to non-detectable levels and removes most precursors. However, historical data from a full-scale potable reuse facility indicates NDMA can form after advanced treatment due to the presence of residual chloramine and NDMA precursors that are not removed during advanced treatment. This study used non-target high-resolution mass spectrometry to identify NDMA precursors and other trace organic compounds during advanced treatment for reuse. Inspection of the total ion chromatograms indicated that there was a substantial reduction of total ionizable compounds by reverse osmosis (RO). The RO feed water contained approximately 22 putative identifications of NDMA precursors across two sampling events. Only one of these precursors was found post-RO and none were found in the subsequent UV/advanced oxidation process (AOP) product water. In addition to the 22 NDMA precursors, the RO feed water contained 41 pharmaceuticals and pesticides that are not likely to be NDMA precursors. Similarly, these compounds were generally well removed by RO. Two compounds with unknown NDMA formation potential, one a suspected benzotriazole trimer with chemical formula C18H16N6O3 and the other with an unassigned formula, were identified in the UV/AOP product water that were not present prior to UV/AOP (after RO), indicating they may be transformation products. Overall, this research demonstrates the utility of non-target analysis for water quality investigations.

Original languageEnglish (US)
Pages (from-to)1944-1955
Number of pages12
JournalEnvironmental Science: Water Research and Technology
Volume4
Issue number12
DOIs
StatePublished - Dec 1 2018

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Reverse osmosis
Mass spectrometry
mass spectrometry
Water
oxidation
Oxidation
water
Disinfection
Pesticides
Water treatment
Organic compounds
disinfection
Drug products
Water quality
Byproducts
reverse osmosis
analysis
Amines
organic compound
water treatment

ASJC Scopus subject areas

  • Environmental Engineering
  • Water Science and Technology

Cite this

Roback, S. L., Ferrer, I., Thurman, E. M., Ishida, K. P., Plumlee, M. H., Poustie, A., ... Hanigan, D. (2018). Non-target mass spectrometry analysis of NDMA precursors in advanced treatment for potable reuse. Environmental Science: Water Research and Technology, 4(12), 1944-1955. https://doi.org/10.1039/c8ew00401c

Non-target mass spectrometry analysis of NDMA precursors in advanced treatment for potable reuse. / Roback, Shannon L.; Ferrer, Imma; Thurman, E. Michael; Ishida, Kenneth P.; Plumlee, Megan H.; Poustie, Andrew; Westerhoff, Paul; Hanigan, David.

In: Environmental Science: Water Research and Technology, Vol. 4, No. 12, 01.12.2018, p. 1944-1955.

Research output: Contribution to journalArticle

Roback, Shannon L. ; Ferrer, Imma ; Thurman, E. Michael ; Ishida, Kenneth P. ; Plumlee, Megan H. ; Poustie, Andrew ; Westerhoff, Paul ; Hanigan, David. / Non-target mass spectrometry analysis of NDMA precursors in advanced treatment for potable reuse. In: Environmental Science: Water Research and Technology. 2018 ; Vol. 4, No. 12. pp. 1944-1955.
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