Non-invasive method to detect the changes of glucose concentration in whole blood using photometric technique

Shiny Amala Priya Rajan, Bruce C. Towe

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A non-invasive method is developed to monitor rapid changes in blood glucose levels in diabetic patients. The system depends on an optical cell built with a LED that emits light of wavelength 535nm, which is a peak absorbance of hemoglobin. As the glucose concentration in blood decreases, its osmolarity also decreases and the Red Blood Cells (RBCs) swell and decrease the path length absorption coefficient. Decreasing absorption coefficient increases the transmission of light through the whole blood. The system was tested with a constructed optical cell that held whole blood in a capillary tube. As expected the light transmitted to the photodiode increases with decreasing glucose concentration. The average response time of the system was between 30-40 seconds.

Original languageEnglish (US)
Title of host publication2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4034-4037
Number of pages4
ISBN (Print)9781424479290
DOIs
StatePublished - Nov 2 2014
Event2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 - Chicago, United States
Duration: Aug 26 2014Aug 30 2014

Other

Other2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
CountryUnited States
CityChicago
Period8/26/148/30/14

Fingerprint

Glucose
Blood
Light
Osmolar Concentration
Reaction Time
Blood Glucose
Hemoglobins
Erythrocytes
Capillary tubes
Hemoglobin
Photodiodes
Light emitting diodes
Cells
Wavelength

ASJC Scopus subject areas

  • Health Informatics
  • Computer Science Applications
  • Biomedical Engineering

Cite this

Rajan, S. A. P., & Towe, B. C. (2014). Non-invasive method to detect the changes of glucose concentration in whole blood using photometric technique. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014 (pp. 4034-4037). [6944509] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2014.6944509

Non-invasive method to detect the changes of glucose concentration in whole blood using photometric technique. / Rajan, Shiny Amala Priya; Towe, Bruce C.

2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., 2014. p. 4034-4037 6944509.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Rajan, SAP & Towe, BC 2014, Non-invasive method to detect the changes of glucose concentration in whole blood using photometric technique. in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014., 6944509, Institute of Electrical and Electronics Engineers Inc., pp. 4034-4037, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, Chicago, United States, 8/26/14. https://doi.org/10.1109/EMBC.2014.6944509
Rajan SAP, Towe BC. Non-invasive method to detect the changes of glucose concentration in whole blood using photometric technique. In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc. 2014. p. 4034-4037. 6944509 https://doi.org/10.1109/EMBC.2014.6944509
Rajan, Shiny Amala Priya ; Towe, Bruce C. / Non-invasive method to detect the changes of glucose concentration in whole blood using photometric technique. 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., 2014. pp. 4034-4037
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