Neural mechanisms of limb position estimation in the primate brain

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Understanding the neural mechanisms of limb position estimation is important both for comprehending the neural control of goal directed arm movements and for developing neuroprosthetic systems designed to replace lost limb function. Here we examined the role of area 5 of the posterior parietal cortex in estimating limb position based on visual and somatic (proprioceptive, efference copy) signals. Single unit recordings were obtained as monkeys reached to visual targets presented in a semi-immersive virtual reality environment. On half of the trials animals were required to maintain their limb position at these targets while receiving both visual and non-visual feedback of their arm position, while on the other trials visual feedback was withheld. When examined individually, many area 5 neurons were tuned to the position of the limb in the workspace but very few neurons modulated their firing rates based on the presence/absence of visual feedback. At the population level however decoding of limb position was somewhat more accurate when visual feedback was provided. These findings support a role for area 5 in limb position estimation but also suggest that visual signals regarding limb position are only weakly represented in this area, and only at the population level.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Pages4060-4063
Number of pages4
DOIs
StatePublished - 2011
Event33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States
Duration: Aug 30 2011Sep 3 2011

Other

Other33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
CountryUnited States
CityBoston, MA
Period8/30/119/3/11

Fingerprint

Primates
Brain
Extremities
Feedback
Sensory Feedback
Neurons
Virtual reality
Decoding
Animals
Arm
Parietal Lobe
Population
Haplorhini

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Shi, Y., & Buneo, C. (2011). Neural mechanisms of limb position estimation in the primate brain. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 4060-4063). [6091009] https://doi.org/10.1109/IEMBS.2011.6091009

Neural mechanisms of limb position estimation in the primate brain. / Shi, Ying; Buneo, Christopher.

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2011. p. 4060-4063 6091009.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shi, Y & Buneo, C 2011, Neural mechanisms of limb position estimation in the primate brain. in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS., 6091009, pp. 4060-4063, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011, Boston, MA, United States, 8/30/11. https://doi.org/10.1109/IEMBS.2011.6091009
Shi Y, Buneo C. Neural mechanisms of limb position estimation in the primate brain. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2011. p. 4060-4063. 6091009 https://doi.org/10.1109/IEMBS.2011.6091009
Shi, Ying ; Buneo, Christopher. / Neural mechanisms of limb position estimation in the primate brain. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2011. pp. 4060-4063
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