Abstract

Hydrophobic platinum(II)-5,10,15,20-tetrakis-(2,3,4,5,6-pentafluorophenyl)-porphyrin (PtTFPP) was physically incorporated into micelles formed from poly(ε-caprolactone)-block-poly(ethylene glycol) to enable the application of PtTFPP in aqueous solution. Micelles were characterized using dynamic light scattering (DLS) and atomic force microscopy (AFM) to show an average diameter of about 140 nm. PtTFPP showed higher quantum efficiency in micellar solution than in tetrahydrofuran (THF) and dichloromethane (CH 2Cl 2). PtTFPP in micelles also exhibited higher photostability than that of PtTFPP suspended in water. PtTFPP in micelles exhibited good oxygen sensitivity and response time. This study provided an efficient approach to enable the application of hydrophobic oxygen sensors in a biological environment.

Original languageEnglish (US)
Article numbere33390
JournalPLoS One
Volume7
Issue number3
DOIs
StatePublished - Mar 22 2012

Fingerprint

Oxygen sensors
platinum
porphyrins
Porphyrins
Micelles
micelles
Platinum
Oxygen
oxygen
atomic force microscopy
Ethylene Glycol
photostability
Atomic Force Microscopy
Methylene Chloride
light scattering
methylene chloride
Dynamic light scattering
polyethylene glycol
Quantum efficiency
Polyethylene glycols

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Nanostructured oxygen sensor - using micelles to incorporate a hydrophobic platinum porphyrin. / Su, Fengyu; Alam, Ruhaniyah; Mei, Qian; Tian, Yanqing; Youngbull, Cody; Johnson, Roger H.; Meldrum, Deirdre.

In: PLoS One, Vol. 7, No. 3, e33390, 22.03.2012.

Research output: Contribution to journalArticle

Su, Fengyu ; Alam, Ruhaniyah ; Mei, Qian ; Tian, Yanqing ; Youngbull, Cody ; Johnson, Roger H. ; Meldrum, Deirdre. / Nanostructured oxygen sensor - using micelles to incorporate a hydrophobic platinum porphyrin. In: PLoS One. 2012 ; Vol. 7, No. 3.
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