@article{1cdf219714d54451b8b5162fc6b940fc,
title = "Myxoma Virus-Loaded Mesenchymal Stem Cells in Experimental Oncolytic Therapy of Murine Pulmonary Melanoma",
abstract = "Myxoma virus construct carrying the IL-15 gene was used to treat experimental pulmonary melanoma in mice. The construct was delivered systemically by mesenchymal stem (“Trojan horse”) cells and triggered an oncolytic effect and antitumor adaptive immune response. This led to marked regression of lesions and makes increased survival possible.",
keywords = "melanoma, mesenchymal stem cells, myxoma virus, oncolytic virotherapy",
author = "Joanna Jazowiecka-Rakus and Aleksander Sochanik and Aleksandra Rusin and Agata Hadry{\'s} and Wojciech Fidyk and Nancy Villa and Rahman, {Masmudur M.} and Ewa Chmielik and Franco, {Lina S.} and Grant McFadden",
note = "Funding Information: The authors thank Krzysztof Rakus for technical guidance and discussion and Mario Abrantes, Marlena Pa{\'z}dzior, Roman Lamch, and Lucyna Ponge for technical assistance. This study was supported by a grant from the National Science Centre , Krak{\'o}w, Poland (no. 2016/22/M/NZ6/00418 ) and by a grant from the International Centre for Genetic Engineering and Biotechnology , Trieste, Italy (no. CRP/POL16-02_EC ). Funding Information: The authors thank Krzysztof Rakus for technical guidance and discussion and Mario Abrantes, Marlena Pa?dzior, Roman Lamch, and Lucyna Ponge for technical assistance. This study was supported by a grant from the National Science Centre, Krak?w, Poland (no. 2016/22/M/NZ6/00418) and by a grant from the International Centre for Genetic Engineering and Biotechnology, Trieste, Italy (no. CRP/POL16-02_EC). Publisher Copyright: {\textcopyright} 2020 The Authors",
year = "2020",
month = sep,
day = "25",
doi = "10.1016/j.omto.2020.07.003",
language = "English (US)",
volume = "18",
pages = "335--350",
journal = "Molecular Therapy - Oncolytics",
issn = "2372-7705",
publisher = "Nature Publishing Group",
}
