Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes

Medicine & Life Sciences

• T-Lymphocyte Epitopes 100%
• Clustered Regularly Interspaced Short Palindromic Repeats 95%
• CRISPR-Associated Protein 9 85%
• Streptococcus pyogenes 67%
• T-Lymphocytes 51%
• Genetic Therapy 51%
• Immunity 45%
• Immunodominant Epitopes 36%
• HLA-A Antigens 34%
• Hydrophobic and Hydrophilic Interactions 30%
• T-Cell Antigen Receptor 28%
• Epigenomics 24%
• Mutation 15%
• Antibodies 15%
• Therapeutics 4%

Physics & Astronomy

• streptococcus 54%
• immunity 38%
• gene therapy 27%
• proteins 26%
• nuclease 25%
• hydrophobicity 20%
• antibodies 19%
• mutations 19%
• preserving 16%
• therapy 15%
• predictions 8%

Chemical Compounds

• Epitope 84%
• Hydrophobicity 35%
• Mutation 35%
• Protein 34%
• Donor 28%
• Application 12%