Molecular systems evaluation of oligomerogenic APP^E693Q and fibrillogenic APP^KM670/671NL/PSEN1^Δexon9 mouse models identifies shared features with human Alzheimer's brain molecular pathology

Medicine & Life Sciences

• Molecular Pathology 100%
• Alzheimer Disease 67%
• Brain 42%
• Amyloid Plaques 23%
• Neurogenesis 23%
• Amyloid 20%
• Transcriptome 20%
• Extracellular Matrix 18%
• Psychological Identification 13%
• Entorhinal Cortex 13%
• Neurons 13%
• RNA Sequence Analysis 12%
• Dentate Gyrus 11%
• Gene Regulatory Networks 11%
• Intellectual Disability 10%
• Transgenic Mice 9%
• Epigenomics 9%
• Exons 9%
• Disease Progression 8%
• Datasets 8%
• Gene Expression 6%
• Proteins 4%
• Therapeutics 1%