Molecular clocks: Four decades of evolution

Sudhir Kumar

Research output: Contribution to journalArticle

201 Citations (Scopus)

Abstract

During the past four decades, the molecular-clock hypothesis has provided an invaluable tool for building evolutionary timescales, and has served as a null model for testing evolutionary and mutation rates in different species. Molecular clocks have also influenced the development of theories of molecular evolution. As DNA-sequencing technologies have progressed, the use of molecular clocks has increased, with a profound effect on our understanding of the temporal diversification of species and genomes.

Original languageEnglish (US)
Pages (from-to)654-662
Number of pages9
JournalNature Reviews Genetics
Volume6
Issue number8
DOIs
StatePublished - Aug 2005

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development theory
Molecular Evolution
Mutation Rate
DNA Sequence Analysis
sequence analysis
Genome
Technology
mutation
genome
testing

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Genetics
  • Genetics(clinical)

Cite this

Molecular clocks : Four decades of evolution. / Kumar, Sudhir.

In: Nature Reviews Genetics, Vol. 6, No. 8, 08.2005, p. 654-662.

Research output: Contribution to journalArticle

Kumar, Sudhir. / Molecular clocks : Four decades of evolution. In: Nature Reviews Genetics. 2005 ; Vol. 6, No. 8. pp. 654-662.
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