Molecular and Cellular Mechanisms for Lipid Synthesis and Accumulation in Microalgae: Biotechnological Implications

Yantao Li, Danxiang Han, Kangsup Yoon, Shunni Zhu, Milton Sommerfeld, Qiang Hu

Research output: Chapter in Book/Report/Conference proceedingChapter

18 Scopus citations

Abstract

Many microalgae have the ability to synthesize and accumulate large amounts of lipids, especially storage neutral lipids, mainly in the form of triacylglycerol (TAG) under environmental stress conditions. TAG and other classes of lipids can be used for fuels, chemicals, and nutraceuticals. This chapter provides the recent progress made in our understanding of the lipid metabolism in eukaryotic microalgae, particularly the function and regulation of the genes and pathways responsible for TAG biosynthesis and the molecular and cellular mechanisms of accumulation of TAG into lipid bodies. Examples of genetic manipulation of the key genes involved in lipid synthesis for strain improvement and the use of lipid metabolism enzymes for potential industrial applications are provided.

Original languageEnglish (US)
Title of host publicationHandbook of Microalgal Culture
Subtitle of host publicationApplied Phycology and Biotechnology: Second Edition
PublisherWiley
Pages545-565
Number of pages21
ISBN (Electronic)9781118567166
ISBN (Print)9780470673898
DOIs
StatePublished - Jan 1 2013

Keywords

  • Kennedy pathway
  • biogenesis
  • diacylglycerol acyltransferase
  • glycerol-3-phosphate acyltransferase
  • lipid bodies
  • lipid synthesis
  • microalgae
  • phospholipid:diacylglycerol acyltransferase
  • triacylglycerol

ASJC Scopus subject areas

  • Engineering(all)
  • Agricultural and Biological Sciences(all)

Fingerprint Dive into the research topics of 'Molecular and Cellular Mechanisms for Lipid Synthesis and Accumulation in Microalgae: Biotechnological Implications'. Together they form a unique fingerprint.

  • Cite this

    Li, Y., Han, D., Yoon, K., Zhu, S., Sommerfeld, M., & Hu, Q. (2013). Molecular and Cellular Mechanisms for Lipid Synthesis and Accumulation in Microalgae: Biotechnological Implications. In Handbook of Microalgal Culture: Applied Phycology and Biotechnology: Second Edition (pp. 545-565). Wiley. https://doi.org/10.1002/9781118567166.ch28