Modeling, synthesis and biological evaluation of potential retinoid‐x‐receptor (Rxr) selective agonists: Analogs of 4‐[1‐(3,5,5,8,8‐pentamethyl‐5,6,7,8‐tetrahyro‐2‐naphthyl)ethynyl]benzoic acid (bexarotene) and 6‐(ethyl(4‐ isobutoxy‐3‐isopropylphenyl)amino)nicotinic acid (net‐4ib)
Peter W. Jurutka, Orsola Di Martino, Sabeeha Reshi, Sanchita Mallick, Zhela L. Sabir, Lech J.P. Staniszewski, Ankedo Warda, Emma L. Maiorella, Ani Minasian, Jesse Davidson, Samir J. Ibrahim, San Raban, Dena Haddad, Madleen Khamisi, Stephanie L. Suban, Bradley J. Dawson, Riley Candia, Joseph W. Ziller, Ming Yue Lee, Chang LiuWei Liu, Pamela A. Marshall, John S. Welch, Carl E. Wagner
Dive into the research topics of 'Modeling, synthesis and biological evaluation of potential retinoid‐x‐receptor (Rxr) selective agonists: Analogs of 4‐[1‐(3,5,5,8,8‐pentamethyl‐5,6,7,8‐tetrahyro‐2‐naphthyl)ethynyl]benzoic acid (bexarotene) and 6‐(ethyl(4‐ isobutoxy‐3‐isopropylphenyl)amino)nicotinic acid (net‐4ib)'. Together they form a unique fingerprint.