Modeling dynamic cellular morphology in images

Xing An, Zhiwen Liu, Yonggang Shi, Ning Li, Yalin Wang, Shantanu H. Joshi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

16 Scopus citations

Abstract

This paper presents a geometric method for modeling dynamic features of cells in image sequences. The morphological changes in cellular membrane boundaries are represented as sequences of parameterized contours. These sequences are analyzed as paths on a shape space equipped with an invariant metric, and matched using dynamic time warping. Experimental results show high sensitivity of the proposed dynamic features to the morphological changes observed in lymphocytes of healthy mice after undergoing skin transplantation when compared with standard representation methods and shape features.

Original languageEnglish (US)
Title of host publicationMedical Image Computing and Computer-Assisted Intervention, MICCAI2012 - 15th International Conference, Proceedings
EditorsNicholas Ayache, Herve Delingette, Polina Golland, Kensaku Mori
PublisherSpringer Verlag
Pages340-347
Number of pages8
ISBN (Print)9783642334146
DOIs
StatePublished - Jan 1 2012
Event15th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2012 - Nice, France
Duration: Oct 1 2012Oct 5 2012

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume7510 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference15th International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2012
CountryFrance
CityNice
Period10/1/1210/5/12

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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  • Cite this

    An, X., Liu, Z., Shi, Y., Li, N., Wang, Y., & Joshi, S. H. (2012). Modeling dynamic cellular morphology in images. In N. Ayache, H. Delingette, P. Golland, & K. Mori (Eds.), Medical Image Computing and Computer-Assisted Intervention, MICCAI2012 - 15th International Conference, Proceedings (pp. 340-347). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 7510 LNCS). Springer Verlag. https://doi.org/10.1007/978-3-642-33415-3_42