Middermal wound healing: A comparison between dermatomal excision and pulsed carbon dioxide laser ablation

H. A. Green, E. Burd, N. S. Nishioka, U. Bruggemann, Carolyn Compton, C. C. Compton

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

Background. - Continuous-wave carbon dioxide lasers are not widely used for the surgical removal of most skin lesions because it is difficult to control laser ablation and the extensive laser-induced thermal damage slows healing. Pulsed lasers provide means to reduce thermal damage produced during laser ablation and permit precise control of tissue removed during ablation. Using a swine model, we compared on a gross and microscopic level the healing of middermal wounds of similar depth and area created by a dermatome and a focused pulsed CO2 laser. Results. - Pulsed CO2 laser ablation removed skin precisely and bloodlessly with 85 ± 15 μm (mean ± SD) of residual thermal damage covering the surface of the wound. Compared with the dermatome, tissue reepithelialization was delayed in the laser wounds at day 3. By day 7, epithelial coverage of the laser-created wounds was not significantly different from the dermatome-created wounds. No significant difference in the appearance of the two wounds was noted at 42 days. Conclusions. - We conclude that the focused pulsed CO2 laser is capable of precisely and bloodlessly ablating skin with conservation of residual subjacent adnexal elements, minimal early interference with epibolic epithelial outgrowth, and no pathologic effects on the wound healing process. Pulsed CO2 lasers may be a valuable instrument for the conservative ablation of skin and skin lesions.

Original languageEnglish (US)
Pages (from-to)639-645
Number of pages7
JournalArchives of Dermatology
Volume128
Issue number5
DOIs
StatePublished - 1992
Externally publishedYes

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Gas Lasers
Laser Therapy
Wound Healing
Lasers
Skin
Wounds and Injuries
Hot Temperature
Swine

ASJC Scopus subject areas

  • Dermatology

Cite this

Middermal wound healing : A comparison between dermatomal excision and pulsed carbon dioxide laser ablation. / Green, H. A.; Burd, E.; Nishioka, N. S.; Bruggemann, U.; Compton, Carolyn; Compton, C. C.

In: Archives of Dermatology, Vol. 128, No. 5, 1992, p. 639-645.

Research output: Contribution to journalArticle

Green, H. A. ; Burd, E. ; Nishioka, N. S. ; Bruggemann, U. ; Compton, Carolyn ; Compton, C. C. / Middermal wound healing : A comparison between dermatomal excision and pulsed carbon dioxide laser ablation. In: Archives of Dermatology. 1992 ; Vol. 128, No. 5. pp. 639-645.
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