Methods in microarray normalization

Phillip Stafford

Research output: Book/ReportBook

24 Citations (Scopus)

Abstract

Scientists can use molecular profiling microarrays to compare healthy cells with their diseased counterparts and develop gene-specific treatments. Finding the best way to interpret original profiling data into accurate trends, however, continues to drive the development of normalization algorithms and software tools. Methods in Microarray Normalization compiles the most useful and novel techniques for the first time into a single, organized source. Experts in the field provide a diverse view of the mathematical processes that are important in normalizing data and avoiding inherent systematic biases. They also review useful software, including discussions on key algorithms, comparative data, and download locations. The book discusses the use of early normalization techniques for new profiling methods and includes strategies for assessing the utility of various normalization algorithms. It presents the latest microarray innovations from companies such as Agilent, Affymetrix, and GeneGo as well as new normalization methods for protein and CGH arrays, many of which are applicable for antibody, microRNA, methylation, and siRNA arrays. Methods in Microarray Normalization provides scientists with a complete resource on the most effective tools available for maximizing microarray data in biochemical research.

Original languageEnglish (US)
PublisherCRC Press
Number of pages305
ISBN (Electronic)9781420052794
ISBN (Print)9781420052787
StatePublished - Jan 1 2008

Fingerprint

Microarrays
Microarray
Normalization
Profiling
Software
Protein Array Analysis
MicroRNAs
Methylation
Small Interfering RNA
MicroRNA
Microarray Data
Software Tools
Antibody
Genes
Innovation
Cells
Antibodies
Continue
Research
Gene

ASJC Scopus subject areas

  • Medicine(all)
  • Mathematics(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Stafford, P. (2008). Methods in microarray normalization. CRC Press.

Methods in microarray normalization. / Stafford, Phillip.

CRC Press, 2008. 305 p.

Research output: Book/ReportBook

Stafford, P 2008, Methods in microarray normalization. CRC Press.
Stafford P. Methods in microarray normalization. CRC Press, 2008. 305 p.
Stafford, Phillip. / Methods in microarray normalization. CRC Press, 2008. 305 p.
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