Metabotropic glutamate receptors: Molecular mechanisms, role in neurological disorders and pharmacological effects

Research output: Book/ReportBook

Abstract

As the most abundant excitatory neurotransmitter in the brain, glutamate plays an important role in numerous aspects of normal and pathological brain function. This book provides an overview of the role of metabotropic glutamate receptors (mGluRs) in basic brain functioning, such as autonomic regulation, synaptic plasticity, and learning and memory. Also provided are up-to-date summaries of recent progress towards identifying how mGluRs both mediate and represent novel pharmacotherapeutic targets for the treatment of various neurological and neuropsychiatric disorders, such as depression, anxiety, schizophrenia, amyloidogenic disorders and substance abuse.

Original languageEnglish (US)
PublisherNova Science Publishers, Inc.
Number of pages239
ISBN (Print)9781631174667, 9781631174513
StatePublished - Jan 1 2014

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Metabotropic Glutamate Receptors
Nervous System Diseases
Pharmacology
Brain
Neuronal Plasticity
Substance-Related Disorders
Neurotransmitter Agents
Glutamic Acid
Schizophrenia
Anxiety
Learning
Depression

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

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