Mediation analysis in psychosomatic medicine research

Ginger Lockhart, David Mackinnon, Vanessa Ohlrich

Research output: Contribution to journalArticle

40 Scopus citations


This article presents an overview of statistical mediation analysis and its application to psychosomatic medicine research. The article begins with a description of the major approaches to mediation analysis and an evaluation of the strengths and limits of each. Emphasis is placed on longitudinal mediation models, and an application using latent growth modeling is presented. The article concludes with a description of recent developments in mediation analysis and suggestions for the use of mediation for future work in psychosomatic medicine research.

Original languageEnglish (US)
Pages (from-to)29-43
Number of pages15
JournalPsychosomatic Medicine
Issue number1
Publication statusPublished - Jan 2011



  • indirect effect
  • mechanism
  • mediation analysis
  • statistical mediation

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Applied Psychology

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