Mechanism of the base-induced decomposition of N-nitroso-N-methylurea

Sidney Hecht, John W. Kozarich

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The mechanism corresponding to the base-induced decomposition of N-nitroso-N-methylurea is discussed. Evidence is presented for the decomposition which is consistent with initial abstraction of a urea proton, but not with a mechanism involving initial nucleophilic addition to the nitroso or carbonyl groups.

Original languageEnglish (US)
Pages (from-to)1821-1824
Number of pages4
JournalJournal of Organic Chemistry
Volume38
Issue number10
StatePublished - 1973
Externally publishedYes

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Decomposition
Urea
Protons
methylurea

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Mechanism of the base-induced decomposition of N-nitroso-N-methylurea. / Hecht, Sidney; Kozarich, John W.

In: Journal of Organic Chemistry, Vol. 38, No. 10, 1973, p. 1821-1824.

Research output: Contribution to journalArticle

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