TY - GEN
T1 - Manipulation of biomolecules using a 3d-printed insulator-based dielectrophoresis device
AU - Rabbani, Mohammad Towshif
AU - Sonker, Mukul
AU - Villarreal, Jorvani Cruz
AU - Ros, Alexandra
N1 - Publisher Copyright:
© 2020 CBMS-0001
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020
Y1 - 2020
N2 - Microfluidics has enabled a wide range of biological and biochemical applications such as high-throughput drug testing, or point of care diagnostics. Insulator-based dielectrophoresis (iDEP) is a non-destructive approach to manipulate biomolecules in a non-uniform electric field that has provided a new dimension for the precise manipulation of biomolecules. Here, we report the first iDEP-based manipulation of biomolecules, namely λ-DNA and phycocyanin within high resolution, 2-photon-polymerization (2pp) 3D-printed microfluidic devices. Our study provides insight into a novel approach of high-resolution 3D-printed microfluidic devices to explore iDEP of many nm-scale biomolecules in the future.
AB - Microfluidics has enabled a wide range of biological and biochemical applications such as high-throughput drug testing, or point of care diagnostics. Insulator-based dielectrophoresis (iDEP) is a non-destructive approach to manipulate biomolecules in a non-uniform electric field that has provided a new dimension for the precise manipulation of biomolecules. Here, we report the first iDEP-based manipulation of biomolecules, namely λ-DNA and phycocyanin within high resolution, 2-photon-polymerization (2pp) 3D-printed microfluidic devices. Our study provides insight into a novel approach of high-resolution 3D-printed microfluidic devices to explore iDEP of many nm-scale biomolecules in the future.
KW - 3D-printing
KW - Biomolecules
KW - Dielectrophoresis
KW - Insulator-based
KW - Microfluidics
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M3 - Conference contribution
AN - SCOPUS:85098256735
T3 - MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 651
EP - 652
BT - MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
T2 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
Y2 - 4 October 2020 through 9 October 2020
ER -