Management of primary biliary cirrhosis and autoimmune cholangitis.

P. Angulo, K. D. Lindor

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Several drugs have been evaluated in the treatment of primary biliary cirrhosis over a number of years. These drugs have immunosuppressive, antiinflammatory, cupruretic, antifibrotic and bile acid properties. Ursodeoxycholic acid has been shown to improve survival free of transplantation in a conclusive fashion. This drug is the single agent that can be recommended for the treatment of primary biliary cirrhosis. Corticosteroid therapy and ursodeoxycholic acid have been evaluated in a few patients with autoimmune cholangitis. This article reviews a large number of studies that have been published assessing different drugs in the treatment of these two entities, particularly in the treatment of primary biliary cirrhosis.

Original languageEnglish (US)
Pages (from-to)333-351, ix
JournalClinics in liver disease
Volume2
Issue number2
DOIs
StatePublished - May 1998
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology

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