MamuSNP: A resource for Rhesus macaque (Macaca mulatta) genomics

Ripan S. Malhi, Brad Sickler, Dawei Lin, Jessica Satkoski, Raul Y. Tito, Debbie George, Sreetharan Kanthaswamy, David Glenn Smith

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

We developed a novel method for identifying SNPs widely distributed throughout the coding and non-coding regions of a genome. The method uses large-scale parallel pyrosequencing technology in combination with bioinformatics tools. We used this method to generate approximately 23,000 candidate SNPs throughout the Macaca mulattagenome. We estimate that over 60% of the SNPs will be of high frequency and useful for mapping QTLs, genetic management, and studies of individual\ relatedness, whereas other less frequent SNPs may be useful as population specific markers for ancestry identification. We have created a web resource called MamuSNP to view the SNPs and associated information online. This resource will also be useful for researchers using a wide variety of Macaca species in their research.

Original languageEnglish (US)
Article numbere438
JournalPLoS One
Volume2
Issue number5
DOIs
StatePublished - May 9 2007
Externally publishedYes

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Bioinformatics
Genomics
Macaca mulatta
Single Nucleotide Polymorphism
Genes
genomics
Macaca
bioinformatics
quantitative trait loci
ancestry
researchers
methodology
Computational Biology
genome
Research Personnel
Genome
Technology
Research
Population

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Malhi, R. S., Sickler, B., Lin, D., Satkoski, J., Tito, R. Y., George, D., ... Smith, D. G. (2007). MamuSNP: A resource for Rhesus macaque (Macaca mulatta) genomics. PLoS One, 2(5), [e438]. https://doi.org/10.1371/journal.pone.0000438

MamuSNP : A resource for Rhesus macaque (Macaca mulatta) genomics. / Malhi, Ripan S.; Sickler, Brad; Lin, Dawei; Satkoski, Jessica; Tito, Raul Y.; George, Debbie; Kanthaswamy, Sreetharan; Smith, David Glenn.

In: PLoS One, Vol. 2, No. 5, e438, 09.05.2007.

Research output: Contribution to journalArticle

Malhi, RS, Sickler, B, Lin, D, Satkoski, J, Tito, RY, George, D, Kanthaswamy, S & Smith, DG 2007, 'MamuSNP: A resource for Rhesus macaque (Macaca mulatta) genomics', PLoS One, vol. 2, no. 5, e438. https://doi.org/10.1371/journal.pone.0000438
Malhi RS, Sickler B, Lin D, Satkoski J, Tito RY, George D et al. MamuSNP: A resource for Rhesus macaque (Macaca mulatta) genomics. PLoS One. 2007 May 9;2(5). e438. https://doi.org/10.1371/journal.pone.0000438
Malhi, Ripan S. ; Sickler, Brad ; Lin, Dawei ; Satkoski, Jessica ; Tito, Raul Y. ; George, Debbie ; Kanthaswamy, Sreetharan ; Smith, David Glenn. / MamuSNP : A resource for Rhesus macaque (Macaca mulatta) genomics. In: PLoS One. 2007 ; Vol. 2, No. 5.
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