MamuSNP: A resource for Rhesus macaque (Macaca mulatta) genomics

Ripan S. Malhi, Brad Sickler, Dawei Lin, Jessica Satkoski, Raul Y. Tito, Debbie George, Sreetharan Kanthaswamy, David Glenn Smith

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

We developed a novel method for identifying SNPs widely distributed throughout the coding and non-coding regions of a genome. The method uses large-scale parallel pyrosequencing technology in combination with bioinformatics tools. We used this method to generate approximately 23,000 candidate SNPs throughout the Macaca mulattagenome. We estimate that over 60% of the SNPs will be of high frequency and useful for mapping QTLs, genetic management, and studies of individual\ relatedness, whereas other less frequent SNPs may be useful as population specific markers for ancestry identification. We have created a web resource called MamuSNP to view the SNPs and associated information online. This resource will also be useful for researchers using a wide variety of Macaca species in their research.

Original languageEnglish (US)
Article numbere438
JournalPloS one
Volume2
Issue number5
DOIs
StatePublished - May 9 2007

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

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