Lower limits of detection for single biological particles using impedance spectroscopy

Pahnit Seriburi; Ashutosh Shastry; Angelique Van't Wout; John Mittler; Shih Hui Chao; John Koschwanez; Deirdre Meldrum

doi:10.1115/nano2005-87060

Lower limits of detection for single biological particles using impedance spectroscopy

Pahnit Seriburi, Ashutosh Shastry, Angelique Van't Wout, John Mittler, Shih Hui Chao, John Koschwanez, Deirdre Meldrum

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Single-cell impedance spectroscopy integrated with lab-on-a-chip systems provides a direct and minimally invasive approach for monitoring and characterizing properties of individual cells in real-time. Here we investigate the theoretical potential and limitations of this technique for analyzing single membrane-bound particles as small as 100 nm in diameter. Our theoretical model suggests a lower limit of detection for single cells on the order of a few microns.

Original language	English (US)
Title of host publication	Proceedings of the 4th ASME Integrated Nanosystems Conference
Subtitle of host publication	Design, Synthesis, and Applications
Publisher	American Society of Mechanical Engineers
Pages	17-18
Number of pages	2
ISBN (Print)	0791842088, 9780791842089
DOIs	https://doi.org/10.1115/nano2005-87060
State	Published - 2005
Externally published	Yes
Event	4th ASME Integrated Nanosystems Conference: Design, Synthesis, and Applications - Berkeley, CA, United States Duration: Sep 14 2005 → Sep 16 2005

Publication series

Name	2005 Proceedings of the 4th ASME Conference on Integrated Nanosystems: Design, Synthesis, and Applications

Other

Other	4th ASME Integrated Nanosystems Conference: Design, Synthesis, and Applications
Country/Territory	United States
City	Berkeley, CA
Period	9/14/05 → 9/16/05

ASJC Scopus subject areas

General Engineering

Access to Document

10.1115/nano2005-87060

Cite this

Seriburi, P., Shastry, A., Van't Wout, A., Mittler, J., Chao, S. H., Koschwanez, J., & Meldrum, D. (2005). Lower limits of detection for single biological particles using impedance spectroscopy. In Proceedings of the 4th ASME Integrated Nanosystems Conference: Design, Synthesis, and Applications (pp. 17-18). (2005 Proceedings of the 4th ASME Conference on Integrated Nanosystems: Design, Synthesis, and Applications). American Society of Mechanical Engineers. https://doi.org/10.1115/nano2005-87060

Lower limits of detection for single biological particles using impedance spectroscopy. / Seriburi, Pahnit; Shastry, Ashutosh; Van't Wout, Angelique et al.
Proceedings of the 4th ASME Integrated Nanosystems Conference: Design, Synthesis, and Applications. American Society of Mechanical Engineers, 2005. p. 17-18 (2005 Proceedings of the 4th ASME Conference on Integrated Nanosystems: Design, Synthesis, and Applications).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Seriburi, P, Shastry, A, Van't Wout, A, Mittler, J, Chao, SH, Koschwanez, J & Meldrum, D 2005, Lower limits of detection for single biological particles using impedance spectroscopy. in Proceedings of the 4th ASME Integrated Nanosystems Conference: Design, Synthesis, and Applications. 2005 Proceedings of the 4th ASME Conference on Integrated Nanosystems: Design, Synthesis, and Applications, American Society of Mechanical Engineers, pp. 17-18, 4th ASME Integrated Nanosystems Conference: Design, Synthesis, and Applications, Berkeley, CA, United States, 9/14/05. https://doi.org/10.1115/nano2005-87060

Seriburi P, Shastry A, Van't Wout A, Mittler J, Chao SH, Koschwanez J et al. Lower limits of detection for single biological particles using impedance spectroscopy. In Proceedings of the 4th ASME Integrated Nanosystems Conference: Design, Synthesis, and Applications. American Society of Mechanical Engineers. 2005. p. 17-18. (2005 Proceedings of the 4th ASME Conference on Integrated Nanosystems: Design, Synthesis, and Applications). doi: 10.1115/nano2005-87060

Seriburi, Pahnit ; Shastry, Ashutosh ; Van't Wout, Angelique et al. / Lower limits of detection for single biological particles using impedance spectroscopy. Proceedings of the 4th ASME Integrated Nanosystems Conference: Design, Synthesis, and Applications. American Society of Mechanical Engineers, 2005. pp. 17-18 (2005 Proceedings of the 4th ASME Conference on Integrated Nanosystems: Design, Synthesis, and Applications).

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abstract = "Single-cell impedance spectroscopy integrated with lab-on-a-chip systems provides a direct and minimally invasive approach for monitoring and characterizing properties of individual cells in real-time. Here we investigate the theoretical potential and limitations of this technique for analyzing single membrane-bound particles as small as 100 nm in diameter. Our theoretical model suggests a lower limit of detection for single cells on the order of a few microns.",

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AU - Koschwanez, John

AU - Meldrum, Deirdre

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AB - Single-cell impedance spectroscopy integrated with lab-on-a-chip systems provides a direct and minimally invasive approach for monitoring and characterizing properties of individual cells in real-time. Here we investigate the theoretical potential and limitations of this technique for analyzing single membrane-bound particles as small as 100 nm in diameter. Our theoretical model suggests a lower limit of detection for single cells on the order of a few microns.

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Lower limits of detection for single biological particles using impedance spectroscopy

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