Low and high frequency fluctuations in center of pressure signals can detect postural deficits in idiopathic Parkinson’s disease patients

Christopher W. Frames, Thurmon Lockhart, Victoria Smith, Markey Olson, Abraham Lieberman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Deterioration of postural control is one of the cardinal symptom in Parkinson’s disease patients. It is also related to their risk of falls and loss of independence. In this study we have explored Empirical Mode Decomposition (EMD) method to unravel the low and high frequency fluctuations in center of pressure (COP) signals collected from standardized Sensory Organization Testing (SOT) in Parkinson’s disease patients. SOT can objectively measure postural control by assessing patient’s ability to effectively use his/her visual, vestibular, and proprioceptive information. A total of sixty Parkinson’s disease patients participated in this study (age = 68.5 ± 9.4; 44 males and 16 females). The participants performed SOT in both the “on” and “off” medication states. We found that fallers have significantly higher fluctuations in medial-lateral direction for SOT condition C6 (p=0.0001) during ON medication state. We also found that fallers have significantly higher weight asymmetric index than non-fallers (p<0.05) during both ON and OFF medication states. We found that Late PD patients have significantly higher high frequency fluctuations for VEST ratio in anterior-posterior (AP) direction (p=0.0031) and also significantly higher high frequency fluctuations in medial-lateral (ML) direction of SOT conditions C5 (p=0.001). We also found that Late PD patients had significantly lower complexity in VEST ratio. Also fallers were found to have significantly lower complexity in VEST ratio (p<0.001). In summary, low and high frequency fluctuations are sensitive measures to detect postural deficits in fallers versus non-fallers and also among early versus late PD patients. Non-linear signal analysis techniques such as EMD can detect peculiar postural deficits in idiopathic Parkinson’s disease patients.

Original languageEnglish (US)
Title of host publication54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017
PublisherInternational Society of Automation (ISA)
Volume2017-March
ISBN (Electronic)9781945541193
StatePublished - Jan 1 2017
Event54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017 - Denver, United States
Duration: Mar 31 2017Apr 1 2017

Other

Other54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017
CountryUnited States
CityDenver
Period3/31/174/1/17

Fingerprint

center of pressure
Parkinson disease
Parkinson Disease
low frequencies
Pressure
Testing
Decomposition
Signal analysis
Deterioration
decomposition
signal analysis
deterioration
Direction compound
Weights and Measures

Keywords

  • Fall risk
  • Parkinson’s disease
  • PD duration
  • Postural stability

ASJC Scopus subject areas

  • Bioengineering
  • Instrumentation
  • Biotechnology
  • Biomedical Engineering

Cite this

Frames, C. W., Lockhart, T., Smith, V., Olson, M., & Lieberman, A. (2017). Low and high frequency fluctuations in center of pressure signals can detect postural deficits in idiopathic Parkinson’s disease patients. In 54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017 (Vol. 2017-March). International Society of Automation (ISA).

Low and high frequency fluctuations in center of pressure signals can detect postural deficits in idiopathic Parkinson’s disease patients. / Frames, Christopher W.; Lockhart, Thurmon; Smith, Victoria; Olson, Markey; Lieberman, Abraham.

54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017. Vol. 2017-March International Society of Automation (ISA), 2017.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Frames, CW, Lockhart, T, Smith, V, Olson, M & Lieberman, A 2017, Low and high frequency fluctuations in center of pressure signals can detect postural deficits in idiopathic Parkinson’s disease patients. in 54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017. vol. 2017-March, International Society of Automation (ISA), 54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017, Denver, United States, 3/31/17.
Frames CW, Lockhart T, Smith V, Olson M, Lieberman A. Low and high frequency fluctuations in center of pressure signals can detect postural deficits in idiopathic Parkinson’s disease patients. In 54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017. Vol. 2017-March. International Society of Automation (ISA). 2017
Frames, Christopher W. ; Lockhart, Thurmon ; Smith, Victoria ; Olson, Markey ; Lieberman, Abraham. / Low and high frequency fluctuations in center of pressure signals can detect postural deficits in idiopathic Parkinson’s disease patients. 54th Annual Rocky Mountain Bioengineering Symposium, RMBS 2017 and 54th International ISA Biomedical Sciences Instrumentation Symposium 2017. Vol. 2017-March International Society of Automation (ISA), 2017.
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abstract = "Deterioration of postural control is one of the cardinal symptom in Parkinson’s disease patients. It is also related to their risk of falls and loss of independence. In this study we have explored Empirical Mode Decomposition (EMD) method to unravel the low and high frequency fluctuations in center of pressure (COP) signals collected from standardized Sensory Organization Testing (SOT) in Parkinson’s disease patients. SOT can objectively measure postural control by assessing patient’s ability to effectively use his/her visual, vestibular, and proprioceptive information. A total of sixty Parkinson’s disease patients participated in this study (age = 68.5 ± 9.4; 44 males and 16 females). The participants performed SOT in both the “on” and “off” medication states. We found that fallers have significantly higher fluctuations in medial-lateral direction for SOT condition C6 (p=0.0001) during ON medication state. We also found that fallers have significantly higher weight asymmetric index than non-fallers (p<0.05) during both ON and OFF medication states. We found that Late PD patients have significantly higher high frequency fluctuations for VEST ratio in anterior-posterior (AP) direction (p=0.0031) and also significantly higher high frequency fluctuations in medial-lateral (ML) direction of SOT conditions C5 (p=0.001). We also found that Late PD patients had significantly lower complexity in VEST ratio. Also fallers were found to have significantly lower complexity in VEST ratio (p<0.001). In summary, low and high frequency fluctuations are sensitive measures to detect postural deficits in fallers versus non-fallers and also among early versus late PD patients. Non-linear signal analysis techniques such as EMD can detect peculiar postural deficits in idiopathic Parkinson’s disease patients.",
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