Longitudinal Research at the Interface of Affective Neuroscience, Developmental Psychopathology, Health and Behavioral Genetics: Findings from the Wisconsin Twin Project

Nicole L. Schmidt, Rebecca J. Brooker, Ian C. Carroll, Jeffrey R. Gagne, Zhan Luo, Elizabeth M. Planalp, Katherine L. Sarkisian, Cory K. Schmidt, Carol A. Van Hulle, Kathryn Lemery-Chalfant, H. H. Goldsmith

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The Wisconsin Twin Project comprises multiple longitudinal studies that span infancy to early adulthood. We summarize recent papers that show how twin designs with deep phenotyping, including biological measures, can inform questions about phenotypic structure, etiology, comorbidity, heterogeneity, and gene-environment interplay of temperamental constructs and mental and physical health conditions of children and adolescents. The general framework for investigations begins with rich characterization of early temperament and follows with study of experiences and exposures across childhood and adolescence. Many studies incorporate neuroimaging and hormone assays.

Original languageEnglish (US)
Pages (from-to)233-239
Number of pages7
JournalTwin Research and Human Genetics
Volume22
Issue number4
DOIs
StatePublished - Aug 1 2019

Keywords

  • behavior genetics
  • developmental psychopathology
  • longitudinal
  • neuroimaging
  • sensory
  • temperament
  • twins

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology
  • Genetics(clinical)

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