Live demonstration: A highly sensitive and quantitative fluorescence sensing platform, for disease diagnosis

Uwadiae Obahiagbon, Joseph T. Smith, Hany Arafa, Dixie E. Kullman, Jennifer Blain Christen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

This Live Demonstration shows a compact, low-cost, disposable fluorescence detection platform, using an LFA test strip or sample cartridge, with up to a 1000-fold enhancement in sensitivity over visual colorimetric readouts. The system achieves a high sensitivity by combining low-cost discrete electronic components with optical interference filters. A sample measurement takes less than a minuite, trading time for accuracy by using a charge integration amplifier. This system is capable of detecting HPV in human sera with a sensitivity of 10 pg/mL [1].

Original languageEnglish (US)
Title of host publicationIEEE International Symposium on Circuits and Systems
Subtitle of host publicationFrom Dreams to Innovation, ISCAS 2017 - Conference Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781467368520
DOIs
StatePublished - Sep 25 2017
Event50th IEEE International Symposium on Circuits and Systems, ISCAS 2017 - Baltimore, United States
Duration: May 28 2017May 31 2017

Other

Other50th IEEE International Symposium on Circuits and Systems, ISCAS 2017
CountryUnited States
CityBaltimore
Period5/28/175/31/17

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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  • Cite this

    Obahiagbon, U., Smith, J. T., Arafa, H., Kullman, D. E., & Blain Christen, J. (2017). Live demonstration: A highly sensitive and quantitative fluorescence sensing platform, for disease diagnosis. In IEEE International Symposium on Circuits and Systems: From Dreams to Innovation, ISCAS 2017 - Conference Proceedings [8050723] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ISCAS.2017.8050723