Linkage of viability genes to marker loci in selfing organisms

Philip W. Hedrick; Outi Muona

doi:10.1038/hdy.1990.8

Linkage of viability genes to marker loci in selfing organisms

Philip W. Hedrick, Outi Muona

Life Sciences, School of (SOLS)

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

Methodology for determining the linkage and effect of viability genes in selfing organisms (both intragametophytic and regular selfing) is developed. The maximum likelihood estimate of the recombination fraction and the selective effect is determined using a progeny array from a heterozygous parent. The method of lod scores, commonly used in human genetics, is applied to this situation. An example from Scots pine is given and the effect of polyembryony and segregation distortion are discussed.

Original language	English (US)
Pages (from-to)	67-72
Number of pages	6
Journal	Heredity
Volume	64
Issue number	1
DOIs	https://doi.org/10.1038/hdy.1990.8
State	Published - Feb 1990

ASJC Scopus subject areas

Genetics
Genetics(clinical)

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10.1038/hdy.1990.8

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title = "Linkage of viability genes to marker loci in selfing organisms",

abstract = "Methodology for determining the linkage and effect of viability genes in selfing organisms (both intragametophytic and regular selfing) is developed. The maximum likelihood estimate of the recombination fraction and the selective effect is determined using a progeny array from a heterozygous parent. The method of lod scores, commonly used in human genetics, is applied to this situation. An example from Scots pine is given and the effect of polyembryony and segregation distortion are discussed.",

author = "Hedrick, {Philip W.} and Outi Muona",

note = "Funding Information: Acknowledgements We thank Dr Veikko Koski of the Finnish Forest Research Institute for providing the selfed seed used in the example. O.M. acknowledges financial support from the Academy of Finland. We thank an anonymous reviewer for comments that added greatly to our final version and to com- ments by J. Ott and F. Sorensen on an earlier version.",

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N2 - Methodology for determining the linkage and effect of viability genes in selfing organisms (both intragametophytic and regular selfing) is developed. The maximum likelihood estimate of the recombination fraction and the selective effect is determined using a progeny array from a heterozygous parent. The method of lod scores, commonly used in human genetics, is applied to this situation. An example from Scots pine is given and the effect of polyembryony and segregation distortion are discussed.

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Linkage of viability genes to marker loci in selfing organisms

Abstract

ASJC Scopus subject areas

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