Life-on-a-chip.

Mary E. Lidstrom, Deirdre Meldrum

Research output: Contribution to journalArticle

137 Citations (Scopus)

Abstract

Mechanistic studies of cellular processes are usually carried out with large populations of cells. However, parameters that are measured as averages of large populations can be misleading. For instance, an apparently linear response to a signal could, in fact, reflect an increasing number of cells in the population that have switched from 'off' to 'on', rather than a graded increase in response by all the cells. At present, the study of single cells is challenging, but new technologies mean it might soon be a reality.

Original languageEnglish (US)
Pages (from-to)158-164
Number of pages7
JournalNature reviews. Microbiology
Volume1
Issue number2
StatePublished - Nov 2003
Externally publishedYes

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Population
Cell Count
Technology

ASJC Scopus subject areas

  • Microbiology

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Lidstrom, M. E., & Meldrum, D. (2003). Life-on-a-chip. Nature reviews. Microbiology, 1(2), 158-164.

Life-on-a-chip. / Lidstrom, Mary E.; Meldrum, Deirdre.

In: Nature reviews. Microbiology, Vol. 1, No. 2, 11.2003, p. 158-164.

Research output: Contribution to journalArticle

Lidstrom, ME & Meldrum, D 2003, 'Life-on-a-chip.', Nature reviews. Microbiology, vol. 1, no. 2, pp. 158-164.
Lidstrom ME, Meldrum D. Life-on-a-chip. Nature reviews. Microbiology. 2003 Nov;1(2):158-164.
Lidstrom, Mary E. ; Meldrum, Deirdre. / Life-on-a-chip. In: Nature reviews. Microbiology. 2003 ; Vol. 1, No. 2. pp. 158-164.
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