Life-history evolution and the polyphenic regulation of somatic maintenance and survival

Thomas Flatt, Gro Amdam, Thomas B L Kirkwood, Stig W. Omholt

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Here we discuss life-history evolution from the perspective of adaptive phenotypic plasticity, with a focus on polyphenisms for somatic maintenance and survival. Polyphenisms are adaptive discrete alternative phenotypes that develop in response to changes in the environment. We suggest that dauer larval diapause and its associated adult phenotypes in the nematode (Caenorhabditis elegans), reproductive dormancy in the fruit fly (Drosophila melanogaster) and other insects, and the worker castes of the honey bee (Apis mellifera) are examples of what may be viewed as the polyphenic regulation of somatic maintenance and survival. In these and other cases, the same genotype can-depending upon its environment-express either of two alternative sets of life-history phenotypes that differ markedly with respect to somatic maintenance, survival ability, and thus life span. This plastic modulation of somatic maintenance and survival has traditionally been underappreciated by researchers working on aging and life history. We review the current evidence for such adaptive life-history switches and their molecular regulation and suggest that they are caused by temporally and/or spatially varying, stressful environments that impose diversifying selection, thereby favoring the evolution of plasticity of somatic maintenance and survival under strong regulatory control. By considering somatic maintenance and survivorship from the perspective of adaptive life-history switches, we may gain novel insights into the mechanisms and evolution of aging.

Original languageEnglish (US)
Pages (from-to)185-218
Number of pages34
JournalQuarterly Review of Biology
Volume88
Issue number3
DOIs
StatePublished - Sep 2013

Fingerprint

Maintenance
life history
phenotype
Bees
Phenotype
Clonal Evolution
Caenorhabditis elegans
fruit flies
phenotypic plasticity
diapause
cans
Honey
Apis mellifera
dormancy
honey bees
Drosophila melanogaster
Social Class
Diptera
plastics
researchers

Keywords

  • Disposable soma
  • Evolution of aging
  • Life history
  • Polyphenism
  • Somatic maintenance
  • Survival

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Life-history evolution and the polyphenic regulation of somatic maintenance and survival. / Flatt, Thomas; Amdam, Gro; Kirkwood, Thomas B L; Omholt, Stig W.

In: Quarterly Review of Biology, Vol. 88, No. 3, 09.2013, p. 185-218.

Research output: Contribution to journalArticle

Flatt, Thomas ; Amdam, Gro ; Kirkwood, Thomas B L ; Omholt, Stig W. / Life-history evolution and the polyphenic regulation of somatic maintenance and survival. In: Quarterly Review of Biology. 2013 ; Vol. 88, No. 3. pp. 185-218.
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