Large global effective population sizes in Paramecium

Margaret S. Snoke, Thomas U. Berendonk, Dana Barth, Michael Lynch

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The genetic effective population size (Ne) of a species is an important parameter for understanding evolutionary dynamics because it mediates the relative effects of selection. However, because most Ne estimates for unicellular organisms are derived either from taxa with poorly understood species boundaries or from host-restricted pathogens and most unicellular species have prominent phases of clonal propagation potentially subject to strong selective sweeps, the hypothesis that Ne is elevated in single-celled organisms remains controversial. Drawing from observations on well-defined species within the genus Paramecium, we report exceptionally high levels of silent-site polymorphism, which appear to be a reflection of large Ne.

Original languageEnglish (US)
Pages (from-to)2474-2479
Number of pages6
JournalMolecular Biology and Evolution
Volume23
Issue number12
DOIs
StatePublished - Dec 1 2006
Externally publishedYes

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Paramecium
effective population size
Population Density
population size
organisms
polymorphism
pathogens
pathogen
organism

Keywords

  • Ciliates
  • Effective population size
  • Genome evolution
  • Mitochondrial DNA
  • Paramecium

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

Cite this

Large global effective population sizes in Paramecium. / Snoke, Margaret S.; Berendonk, Thomas U.; Barth, Dana; Lynch, Michael.

In: Molecular Biology and Evolution, Vol. 23, No. 12, 01.12.2006, p. 2474-2479.

Research output: Contribution to journalArticle

Snoke, Margaret S. ; Berendonk, Thomas U. ; Barth, Dana ; Lynch, Michael. / Large global effective population sizes in Paramecium. In: Molecular Biology and Evolution. 2006 ; Vol. 23, No. 12. pp. 2474-2479.
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